Cigna Specialty Care Options programs: Changes to the drug list

April 14, 2026

The Cigna Specialty Care Options® and Cigna Specialty Care Options Plus® programs identify customers whose nononcology and oncology specialty medications are being administered in a higher-intensity setting (e.g., outpatient hospital) to determine whether a less-intensive site of care is clinically appropriate. These customers are identified at the time of prior authorization.

Cigna Healthcare recently expanded the Specialty Care Options and Specialty Care Options Plus drug list to include the specialty medical injectables listed below.

Specialty Care Options Program

NameGeneric NameEffective Date
QIVIGY®immune globulin intravenous, human-khtmMarch 9, 2026
LOARGYS®pegzeilarginase-nblnMarch 23, 2026
ADVATE®1antihemophilic factor [recombinant]July 1, 2026
ADYNOVATE®1antihemophilic factor [recombinant]July 1, 2026
AFSTYLA®1antihemophilic factor [recombinant]July 1, 2026
ALPHANATE®1antihemophilic factor/von Willebrand factor complex [human]July 1, 2026
AlphaNine®1coagulation factor IX [human]July 1, 2026
ALPROLIX®1coagulation factor IX [recombinant]July 1, 2026
ALTUVIIIO®1antihemophilic factor [recombinant]July 1, 2026
BeneFIX®1coagulation factor IX [recombinant]July 1, 2026
COAGADEX®1coagulation factor X [human]July 1, 2026
ELOCTATE®1antihemophilic factor [recombinant]July 1, 2026
ESPEROCT®1antihemophilic factor [recombinant]July 1, 2026
FEIBA1anti-inhibitor coagulant complexJuly 1, 2026
HEMOFIL®1 Mantihemophilic factor [human]July 1, 2026
Hemophilia Clot Factor NOC1July 1, 2026
Humate-P®1antihemophilic factor/von Willebrand factor complex [human]July 1, 2026
IDELVION®1coagulation factor IX [recombinant]July 1, 2026
IXINITY®1coagulation factor IX [recombinant]July 1, 2026
JIVI®1antihemophilic factor [recombinant]July 1, 2026
KOĀTE1antihemophilic factor [human]July 1, 2026
KOGENATE1antihemophilic factor [recombinant]July 1, 2026
KOVALTRY®1antihemophilic factor [recombinant]July 1, 2026
NOVOEIGHT®1antihemophilic factor [recombinant]July 1, 2026
NOVOSEVEN®1 RTcoagulation factor VIIa [recombinant]July 1, 2026
NUWIQ®1antihemophilic factor [recombinant]July 1, 2026
 OBIZUR1antihemophilic factor [recombinant]July 1, 2026
Profilnine®1 SDcoagulation factor IX [human]July 1, 2026
REBINYN®1coagulation factor IX [recombinant]July 1, 2026
RIXUBIS1coagulation factor IX [recombinant]July 1, 2026
SEVENFACT®1coagulation factor VIIa [recombinant]July 1, 2026
TRETTEN®1coagulation factor XIII A-subunit [recombinant]July 1, 2026
VONVENDI®1von Willebrand factor [recombinant]July 1, 2026
WILATE1antihemophilic factor/von Willebrand factor complex [human]July 1, 2026
XYNTHA®1antihemophilic factor [recombinant]July 1, 2026

1Effective January 1, 2027 for Individual & Family Plans.

Specialty Care Options Plus program

NameGeneric NameEffective Date
AUKELSOTMdenosumab-kyqqApril 1, 2026
BLINCYTO®1blinatumomabJuly 1, 2026

1Effective January 1, 2027 for Individual & Family Plans.

Additional information

To access the Specialty Care Options and Specialty Care Options Plus drug list, log in to the Cigna for Health Care Professionals website (CignaforHCP.com) and go to Resources > Reimbursement and Payment Policies > Precertification Policies > Specialty Care Options and Specialty Care Options Plus list. We recommend you review this list frequently, as it is subject to change. New-to-market specialty medical injectables may be added upon U.S. Food and Drug Administration approval.

The Specialty Care Options and Specialty Care Options Plus programs contain a medical necessity site-of-care review in accordance with our Medication Administration Site of Care coverage policy.

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