April 14, 2026
The Cigna Specialty Care Options® and Cigna Specialty Care Options Plus® programs identify customers whose nononcology and oncology specialty medications are being administered in a higher-intensity setting (e.g., outpatient hospital) to determine whether a less-intensive site of care is clinically appropriate. These customers are identified at the time of prior authorization.
Cigna Healthcare recently expanded the Specialty Care Options and Specialty Care Options Plus drug list to include the specialty medical injectables listed below.
Specialty Care Options Program
| Name | Generic Name | Effective Date |
| QIVIGY® | immune globulin intravenous, human-khtm | March 9, 2026 |
| LOARGYS® | pegzeilarginase-nbln | March 23, 2026 |
| ADVATE®1 | antihemophilic factor [recombinant] | July 1, 2026 |
| ADYNOVATE®1 | antihemophilic factor [recombinant] | July 1, 2026 |
| AFSTYLA®1 | antihemophilic factor [recombinant] | July 1, 2026 |
| ALPHANATE®1 | antihemophilic factor/von Willebrand factor complex [human] | July 1, 2026 |
| AlphaNine®1 | coagulation factor IX [human] | July 1, 2026 |
| ALPROLIX®1 | coagulation factor IX [recombinant] | July 1, 2026 |
| ALTUVIIIO®1 | antihemophilic factor [recombinant] | July 1, 2026 |
| BeneFIX®1 | coagulation factor IX [recombinant] | July 1, 2026 |
| COAGADEX®1 | coagulation factor X [human] | July 1, 2026 |
| ELOCTATE®1 | antihemophilic factor [recombinant] | July 1, 2026 |
| ESPEROCT®1 | antihemophilic factor [recombinant] | July 1, 2026 |
| FEIBA1 | anti-inhibitor coagulant complex | July 1, 2026 |
| HEMOFIL®1 M | antihemophilic factor [human] | July 1, 2026 |
| Hemophilia Clot Factor NOC1 | July 1, 2026 | |
| Humate-P®1 | antihemophilic factor/von Willebrand factor complex [human] | July 1, 2026 |
| IDELVION®1 | coagulation factor IX [recombinant] | July 1, 2026 |
| IXINITY®1 | coagulation factor IX [recombinant] | July 1, 2026 |
| JIVI®1 | antihemophilic factor [recombinant] | July 1, 2026 |
| KOĀTE1 | antihemophilic factor [human] | July 1, 2026 |
| KOGENATE1 | antihemophilic factor [recombinant] | July 1, 2026 |
| KOVALTRY®1 | antihemophilic factor [recombinant] | July 1, 2026 |
| NOVOEIGHT®1 | antihemophilic factor [recombinant] | July 1, 2026 |
| NOVOSEVEN®1 RT | coagulation factor VIIa [recombinant] | July 1, 2026 |
| NUWIQ®1 | antihemophilic factor [recombinant] | July 1, 2026 |
| OBIZUR1 | antihemophilic factor [recombinant] | July 1, 2026 |
| Profilnine®1 SD | coagulation factor IX [human] | July 1, 2026 |
| REBINYN®1 | coagulation factor IX [recombinant] | July 1, 2026 |
| RIXUBIS1 | coagulation factor IX [recombinant] | July 1, 2026 |
| SEVENFACT®1 | coagulation factor VIIa [recombinant] | July 1, 2026 |
| TRETTEN®1 | coagulation factor XIII A-subunit [recombinant] | July 1, 2026 |
| VONVENDI®1 | von Willebrand factor [recombinant] | July 1, 2026 |
| WILATE1 | antihemophilic factor/von Willebrand factor complex [human] | July 1, 2026 |
| XYNTHA®1 | antihemophilic factor [recombinant] | July 1, 2026 |
1Effective January 1, 2027 for Individual & Family Plans.
Specialty Care Options Plus program
| Name | Generic Name | Effective Date |
| AUKELSOTM | denosumab-kyqq | April 1, 2026 |
| BLINCYTO®1 | blinatumomab | July 1, 2026 |
1Effective January 1, 2027 for Individual & Family Plans.
Additional information
To access the Specialty Care Options and Specialty Care Options Plus drug list, log in to the Cigna for Health Care Professionals website (CignaforHCP.com) and go to Resources > Reimbursement and Payment Policies > Precertification Policies > Specialty Care Options and Specialty Care Options Plus list. We recommend you review this list frequently, as it is subject to change. New-to-market specialty medical injectables may be added upon U.S. Food and Drug Administration approval.
The Specialty Care Options and Specialty Care Options Plus programs contain a medical necessity site-of-care review in accordance with our Medication Administration Site of Care coverage policy.
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