Pharmacy update: Alternative medication available due to UDENYCA supply interruption

October 11, 2024

There is a temporary manufacturing shortage of the drug UDENYCA® (pegfilgrastim-cbqv). As a result, we have approved the use of NYVEPRIA™ as an alternative medication when a prior authorization for UDENYCA is already on file for a patient with Cigna HealthcareSM coverage. The manufacturer expects the supply interruption to be solved by early November. NYVEPRIA is approved as an alternative through December 31, 2024.

What this means

  • Providers are not required to obtain a new prior authorization when prescribing NYVEPRIA as an alternative.
  • Providers are required to follow the standard prior authorization process to prescribe any other alternative medications.

Additional information

The following chart details the current status and Healthcare Common Procedure Coding System (HCPCS) codes for UDENYCA and alternative medications.

Drug brand nameGeneric drug nameHCPCS codeCurrent status
UDENYCA®pegfilgrastim-cbqvQ5111Supply interruption at the manufacturer
UDENYCA® Autoinjectorpegfilgrastim-cbqvQ5111Supply interruption at the manufacturer
UDENYCA® ON-BODY Injectorpegfilgrastim-cbqvQ5111Supply interruption at the manufacturer
NYVEPRIA™pegfilgrastim-apgfQ5122Approved UDENYCA® alternative
Fulphila®pegfilgrastim-jmdbQ5108Standard prior authorization required
Fylnetra®pegfilgrastim-pbbkQ5130Standard prior authorization required
Neulasta® Onpro®pegfilgrastimJ2506Standard prior authorization required
Neulasta® InjectionpegfilgrastimJ2506Standard prior authorization required
STIMUFEND®pegfilgrastim-fpgkQ5127Standard prior authorization required
Ziextenzo®pegfilgrastim-bmezQ5120Standard prior authorization required

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